The Atchison, Topeka and Santa Fe Passenger and Freight Complex is a nationally recognized historic district in Fort Madison, Iowa, listed on the National Register of Historic Places since 1992. The district, featuring three significant buildings constructed over a 24-year span, reflects the architectural styles of their respective eras.

The complex includes:

• The 1910 Passenger Depot: Designed by C.F. Morse in the Mission Revival style, this single-story brick building, originally serving both passenger and freight needs, was adapted from the railroad’s "county-seat" standard. It boasts a distinctive red tile hipped roof and Appanoose stone detailing. A 1945 renovation introduced Art Deco elements, including the removal of the women’s waiting room.

• The 1922 Railway Express Office: Designed by J.M. Dunham, this building also features Mission Revival architecture but with distinct copper detailing that was later removed in a 1990 renovation. It complements the passenger depot with its pressed brick and stone trim.

• The 1934 Santa Fe Freight Office: Located west of the Railway Express Office, this two-story brick structure is more utilitarian in design, featuring the Santa Fe logo in stone on its elevations. It served as a crucial part of the railroad’s operations, including facilities for crew rest.

The complex, once a key stop on the Santa Fe Railway's only Iowa route and a hub for locomotive repairs, now hosts the North Lee County Historical Society, the Fort Madison Tourism Bureau, and the Fort Madison Amtrak ticket office. The original passenger depot was replaced by the Amtrak station in 1968, and service returned to the restored station in 2021.

ATSF DEPOT